Nicotinamide Deteriorates Post-Stroke Immunodepression Following Cerebral Ischemia–Reperfusion Injury in Mice

(1) Background: Inducing experimental stroke leads to biphasic immune responses, where the early activation of immune functions is followed by severe immunosuppression accompanied by spleen and thymus atrophy. Nicotinamide, a water-soluble B-group vitamin, is a known neuroprotectant against brain is...

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Bibliographic Details
Main Authors: Shih-Huang Tai, Liang-Chun Chao, Sheng-Yang Huang, Hsiao-Wen Lin, Ai-Hua Lee, Yi-Yun Chen, E-Jian Lee
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/8/2145