Angiotensin-Converting Enzyme (ACE) Inhibitors May Moderate COVID-19 Hyperinflammatory Response: An Observational Study with Deep Immunophenotyping

Background: Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin-II receptor blockers (ARB), the most commonly prescribed antihypertensive medications, counter renin-angiotensin-aldosterone system (RAAS) activation via induction of angiotensin-converting enzyme 2 (ACE2) expression. Consid...

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Bibliographic Details
Main Authors: Venkata R. Duvvuri, Andrew Baumgartner, Sevda Molani, Patricia V. Hernandez, Dan Yuan, Ryan T. Roper, Wanessa F. Matos, Max Robinson, Yapeng Su, Naeha Subramanian, Jason D. Goldman, James R. Heath, Jennifer J. Hadlock
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-01-01
Series:Health Data Science
Online Access:https://spj.science.org/doi/10.34133/hds.0002