Extracting multi-way chromatin contacts from Hi-C data.

There is a growing realization that multi-way chromatin contacts formed in chromosome structures are fundamental units of gene regulation. However, due to the paucity and complexity of such contacts, it is challenging to detect and identify them using experiments. Based on an assumption that chromos...

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Bibliographic Details
Main Authors: Lei Liu, Bokai Zhang, Changbong Hyeon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009669&type=printable