Cytoplasmic Localization of Thyroid Hormone Receptor (TR) Alpha and Nuclear Expression of Its Isoform TRα2 Determine Survival in Breast Cancer in Opposite Ways

Cytoplasmic Localization of Thyroid Hormone Receptor (TR) Alpha and Nuclear Expression of Its Isoform TRα2 Determine Survival in Breast Cancer in Opposite Ways

The aim of this retrospective study was to assess the respective prognostic values of cytoplasmic and nuclear TRα, TRα1, and TRα2 expression in breast cancer (BC) tissue samples and correlate the results with clinico-pathological parameters. In 249 BC patients, the expression patterns of general TRα...

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Bibliographic Details
Main Authors: Mariella Schneider, Melitta B. Köpke, Alaleh Zati zehni, Theresa Vilsmaier, Mirjana Kessler, Magdalena Kailuweit, Aurelia Vattai, Helene Hildegard Heidegger, Vincent Cavaillès, Udo Jeschke, Nina Ditsch
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
breast cancer
thyroid hormone receptor
TRα
TRα1
TRα2
subcellular localization
Online Access:https://www.mdpi.com/2072-6694/15/14/3610

Internet

https://www.mdpi.com/2072-6694/15/14/3610

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