A Missense Variant in CASKIN1’s Proline-Rich Region Segregates with Psychosis in a Three-Generation Family
The polygenic nature of schizophrenia (SCZ) implicates many variants in disease development. Rare variants of high penetrance have been shown to contribute to the disease prevalence. Whole-exome sequencing of a large three-generation family with SCZ and bipolar disorder identified a single segregati...
Main Authors: | Marah H. Wahbeh, Xi Peng, Sofia Bacharaki, Alexandros Hatzimanolis, Stefanos Dimitrakopoulos, Elizabeth Wohler, Xue Yang, Christian Yovo, Brady J. Maher, Nara Sobreira, Nikos C. Stefanis, Dimitrios Avramopoulos |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/14/1/177 |
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