Dual-scRNA-seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection

Dual-scRNA-seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection

Summary: Although phagocytic cells are documented targets of Leishmania parasites, it is unclear whether other cell types can be infected. Here, we use unbiased single-cell RNA sequencing (scRNA-seq) to simultaneously analyze host cell and Leishmania donovani transcriptomes to identify and annotate...

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Bibliographic Details
Main Authors: Konstantinos Karagiannis, Sreenivas Gannavaram, Chaitenya Verma, Thalia Pacheco-Fernandez, Parna Bhattacharya, Hira L. Nakhasi, Abhay R. Satoskar
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011087

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http://www.sciencedirect.com/science/article/pii/S2211124723011087

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