Dual-scRNA-seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection
Summary: Although phagocytic cells are documented targets of Leishmania parasites, it is unclear whether other cell types can be infected. Here, we use unbiased single-cell RNA sequencing (scRNA-seq) to simultaneously analyze host cell and Leishmania donovani transcriptomes to identify and annotate...
Main Authors: | Konstantinos Karagiannis, Sreenivas Gannavaram, Chaitenya Verma, Thalia Pacheco-Fernandez, Parna Bhattacharya, Hira L. Nakhasi, Abhay R. Satoskar |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723011087 |
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