Safety and immunogenicity of H5N1 influenza vaccine based on baculovirus surface display system of Bombyx mori.

Avian influenza virus (H5N1) has caused serious infections in human beings. This virus has the potential to emerge as a pandemic threat in humans. Effective vaccines against H5N1 virus are needed. A recombinant Bombyx mori baculovirus, Bmg64HA, was constructed for the expression of HA protein of H5N...

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Bibliographic Details
Main Authors: Rongzhong Jin, Zhengbing Lv, Qin Chen, Yanping Quan, Haihua Zhang, Si Li, Guogang Chen, Qingliang Zheng, Lairong Jin, Xiangfu Wu, Jianguo Chen, Yaozhou Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2592543?pdf=render