Copper homeostasis and cuproptosis in atherosclerosis: metabolism, mechanisms and potential therapeutic strategies

Abstract Copper is an essential micronutrient that plays a pivotal role in numerous physiological processes in virtually all cell types. Nevertheless, the dysregulation of copper homeostasis, whether towards excess or deficiency, can lead to pathological alterations, such as atherosclerosis. With th...

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Bibliographic Details
Main Authors: Shengjie Yang, Yujuan Li, Lijun Zhou, Xinyue Wang, Longtao Liu, Min Wu
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01796-1