Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> D39

Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> D39

ABSTRACT The catalase-negative, facultative anaerobe Streptococcus pneumoniae D39 is naturally resistant to hydrogen peroxide (H2O2) produced endogenously by pyruvate oxidase (SpxB). Here, we investigate the adaptive response to endogenously produced H2O2. We show that lactate oxidase, which convert...

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Bibliographic Details
Main Authors: John P. Lisher, Ho-Ching Tiffany Tsui, Smirla Ramos-Montañez, Kristy L. Hentchel, Julia E. Martin, Jonathan C. Trinidad, Malcolm E. Winkler, David P. Giedroc
Format: Article
Language:English
Published: American Society for Microbiology 2017-02-01
Series:mSphere
Subjects:
Streptococcus pneumoniae
hydrogen peroxide stress
pyruvate oxidase
sulfenylation
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00291-16

Internet

https://journals.asm.org/doi/10.1128/mSphere.00291-16

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