Differential Regulation of POC5 by ERα in Human Normal and Scoliotic Cells

Differential Regulation of POC5 by ERα in Human Normal and Scoliotic Cells

Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional spinal deformity. The incidence of AIS in females is 8.4 times higher than in males. Several hypotheses on the role of estrogen have been postulated for the progression of AIS. Recently, Centriolar protein gene POC5 (<i>POC5&...

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Bibliographic Details
Main Authors: Amani Hassan, Edward T. Bagu, Shunmoogum A. Patten, Sirinart Molidperee, Stefan Parent, Soraya Barchi, Isabelle Villemure, André Tremblay, Florina Moldovan
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Genes
Subjects:
puberty
POC5
17β-estradiol
estrogen
E2
osteoblasts
Online Access:https://www.mdpi.com/2073-4425/14/5/1111

Internet

https://www.mdpi.com/2073-4425/14/5/1111

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