Crotalaria ferruginea extract attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting MAPK/NF-κB signaling pathways

Crotalaria ferruginea extract attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting MAPK/NF-κB signaling pathways

Objective: To evaluate the anti-inflammatory activity of Crotalaria ferruginea extract (CFE) and its mechanism. Methods: An intratracheal lipopolysaccharide (LPS) instillation-induced acute lung injury (ALI) model was used to study the anti-inflammatory activity of CFE in vivo. The LPS-induced shock...

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Bibliographic Details
Main Authors: Wei Pan, Li-Ping Meng, Jie Su, Zheng-Biao Yang, Wei-Feng Du, Zhi-Wei Xu, Yun-Xiang Chen, Sheng Zhang, Feng Xie, Cong Xu, Hong-Zhong Yang, Wei-Hong Ge
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
crotalaria ferruginea; acute lung injury; cytokine; lipopolysaccharide; nuclear factor-κb; mitogen-activated protein kinase
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=11;spage=481;epage=490;aulast=Pan

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=11;spage=481;epage=490;aulast=Pan

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