Implications of Peptidyl Arginine Deiminase 4 gene transcription and polymorphisms in susceptibility to rheumatoid arthritis in an Iranian population

Implications of Peptidyl Arginine Deiminase 4 gene transcription and polymorphisms in susceptibility to rheumatoid arthritis in an Iranian population

Abstract Background Peptidyl arginine deiminase 4 (PADI4) has been implicated in Rheumatoid arthritis (RA) pathogenesis. Here we aimed to evaluate the association of PADI4 gene rs11203367 and rs1748033 single nucleotide polymorphisms (SNPs) with RA proneness. Methods The mRNA expression of PADI4 was...

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Bibliographic Details
Main Authors: Zahra Bagheri-Hosseinabadi, Mohammad Reza Mirzaei, Ozrasadat Esmaeili, Fatemeh Asadi, Hassan Ahmadinia, Banafshe Shamsoddini, Mitra Abbasifard
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Medical Genomics
Subjects:
Rheumatoid arthritis
Peptidyl arginine deiminase 4
Single nucleotide polymorphism
Genetic association
Online Access:https://doi.org/10.1186/s12920-023-01532-9

Internet

https://doi.org/10.1186/s12920-023-01532-9

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