PD1+ Treg cell remodeling promotes immune homeostasis within peripheral blood and tumor microenvironment after microparticles-transarterial chemoembolization in hepatocellular carcinoma

PD1+ Treg cell remodeling promotes immune homeostasis within peripheral blood and tumor microenvironment after microparticles-transarterial chemoembolization in hepatocellular carcinoma

Abstract The effects of transarterial chemoembolization (TACE) on the systemic immune in hepatocellular carcinoma (HCC) are not well understood. We aimed to reveal the temporal and spatial changes in the immune profile of peripheral blood and tumor tissues in HCC patients following TACE. Eighty-four...

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Bibliographic Details
Main Authors: Zhizhong Ren, Yaqin Wang, Dandan Jiang, Ying Liu, Xiaowei Yang, Tianxiao Wang, Junqi Zhu, Wenya Wang, Qian Chen, Yuewei Zhang
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Hepatocellular carcinoma
Microparticles-transarterial chemoembolization
PD1+ Treg
PD1+ CD8+ T cell
Tumor microenvironment
Online Access:https://doi.org/10.1007/s00262-025-03962-z

Internet

https://doi.org/10.1007/s00262-025-03962-z

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