Distinct mechanisms of loss of IFN-gamma mediated HLA class I inducibility in two melanoma cell lines

<p>Abstract</p> <p>Background</p> <p>The inability of cancer cells to present antigen on the cell surface via MHC class I molecules is one of the mechanisms by which tumor cells evade anti-tumor immunity. Alterations of Jak-STAT components of interferon (IFN)-mediated s...

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Bibliographic Details
Main Authors: Garrido Federico, Aptsiauri Natalia, Jiménez Pilar, Del Campo Ana, Méndez Rosa, Rodríguez Teresa, Ruiz-Cabello Francisco
Format: Article
Language:English
Published: BMC 2007-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/34