Exosome Treatment Enhances Anti-Inflammatory M2 Macrophages and Reduces Inflammation-Induced Pyroptosis in Doxorubicin-Induced Cardiomyopathy

Exosome Treatment Enhances Anti-Inflammatory M2 Macrophages and Reduces Inflammation-Induced Pyroptosis in Doxorubicin-Induced Cardiomyopathy

Doxorubicin (Dox) is an effective antineoplastic agent used to treat cancers, but its use is limited as Dox induces adverse cardiotoxic effects. Dox-induced cardiotoxicity (DIC) can lead to heart failure and death. There is no study that investigates whether embryonic stem cell-derived exosomes (ES-...

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Bibliographic Details
Main Authors: Dinender K. Singla, Taylor A. Johnson, Zahra Tavakoli Dargani
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
doxorubicin
cardiotoxicity
pyroptosis
inflammation
embryonic stem cells
exosomes
Online Access:https://www.mdpi.com/2073-4409/8/10/1224

Internet

https://www.mdpi.com/2073-4409/8/10/1224

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