Interstitial pneumonitis associated with combined regimen of immunotherapy and conventional therapies—pharmacovigilance database analysis with real-world data validation

Interstitial pneumonitis associated with combined regimen of immunotherapy and conventional therapies—pharmacovigilance database analysis with real-world data validation

Abstract Background Immune checkpoint inhibitor (ICI) therapy combined with conventional therapies is being broadly applied in non-small cell lung cancer (NSCLC) patients. However, the risk of interstitial pneumonitis (IP) following a combined regimen is incompletely characterized. Methods A total o...

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Bibliographic Details
Main Authors: Xue-Jun Guo, Xiao-Ting Cai, Zi-Xuan Rong, Yan-Pei Zhang, Yu-Xiang Wen, Xue Bai, Jian Wang, Qiang John Fu, Ze-Qin Guo, Li-Li Long, Si-Cong Ma, Xin-Ran Tang, Li Liu, Jian Guan, Zhong-Yi Dong, De-Hua Wu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Medicine
Subjects:
Interstitial pneumonitis
Non-small cell lung cancer
Immune checkpoint inhibitors
Radiation therapy
Conventional therapy
Online Access:https://doi.org/10.1186/s12916-022-02713-6

Internet

https://doi.org/10.1186/s12916-022-02713-6

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