The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases
<i>Nigella sativa</i> L. is an herb that is commonly used in cooking and in traditional medicine, particularly in Arab countries, the Indian subcontinent, and some areas of eastern Europe. <i>Nigella sativa</i> is also called “black cumin” or “black seeds”, as the seeds are t...
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| Format: | Article |
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MDPI AG
2024-02-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/12/2/405 |
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| author | Giuseppe Derosa Angela D’Angelo Pamela Maffioli Laura Cucinella Rossella Elena Nappi |
| author_facet | Giuseppe Derosa Angela D’Angelo Pamela Maffioli Laura Cucinella Rossella Elena Nappi |
| author_sort | Giuseppe Derosa |
| collection | DOAJ |
| description | <i>Nigella sativa</i> L. is an herb that is commonly used in cooking and in traditional medicine, particularly in Arab countries, the Indian subcontinent, and some areas of eastern Europe. <i>Nigella sativa</i> is also called “black cumin” or “black seeds”, as the seeds are the most-used part of the plant. They contain the main bioactive component thymoquinone (TQ), which is responsible for the pleiotropic pharmacological properties of the seeds, including anti-oxidant, anti-inflammatory, anti-hypertensive, anti-hepatotoxic, hypoglycemic, and lipid-lowering properties. In this narrative review, both the potential mechanisms of action of <i>Nigella sativa</i> and the fundamental role played by pharmaceutical technology in optimizing preparations based on this herb in terms of yield, quality, and effectiveness have been outlined. Moreover, an analysis of the market of products containing <i>Nigella sativa</i> was carried out based on the current literature with an international perspective, along with a specific focus on Italy. |
| first_indexed | 2024-03-07T22:40:51Z |
| format | Article |
| id | doaj.art-9b36f25110a5418bb790766ada0e7875 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-07T22:40:51Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-9b36f25110a5418bb790766ada0e78752024-02-23T15:08:44ZengMDPI AGBiomedicines2227-90592024-02-0112240510.3390/biomedicines12020405The Use of <i>Nigella sativa</i> in Cardiometabolic DiseasesGiuseppe Derosa0Angela D’Angelo1Pamela Maffioli2Laura Cucinella3Rossella Elena Nappi4Department of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, ItalyDepartment of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, ItalyCentre of Diabetes, Metabolic Diseases, and Dyslipidemias, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy<i>Nigella sativa</i> L. is an herb that is commonly used in cooking and in traditional medicine, particularly in Arab countries, the Indian subcontinent, and some areas of eastern Europe. <i>Nigella sativa</i> is also called “black cumin” or “black seeds”, as the seeds are the most-used part of the plant. They contain the main bioactive component thymoquinone (TQ), which is responsible for the pleiotropic pharmacological properties of the seeds, including anti-oxidant, anti-inflammatory, anti-hypertensive, anti-hepatotoxic, hypoglycemic, and lipid-lowering properties. In this narrative review, both the potential mechanisms of action of <i>Nigella sativa</i> and the fundamental role played by pharmaceutical technology in optimizing preparations based on this herb in terms of yield, quality, and effectiveness have been outlined. Moreover, an analysis of the market of products containing <i>Nigella sativa</i> was carried out based on the current literature with an international perspective, along with a specific focus on Italy.https://www.mdpi.com/2227-9059/12/2/405<i>Nigella sativa</i>thymoquinonepharmacological properties |
| spellingShingle | Giuseppe Derosa Angela D’Angelo Pamela Maffioli Laura Cucinella Rossella Elena Nappi The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases Biomedicines <i>Nigella sativa</i> thymoquinone pharmacological properties |
| title | The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases |
| title_full | The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases |
| title_fullStr | The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases |
| title_full_unstemmed | The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases |
| title_short | The Use of <i>Nigella sativa</i> in Cardiometabolic Diseases |
| title_sort | use of i nigella sativa i in cardiometabolic diseases |
| topic | <i>Nigella sativa</i> thymoquinone pharmacological properties |
| url | https://www.mdpi.com/2227-9059/12/2/405 |
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