De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report

De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report

Here, the authors identify and validate the emergence of a SARS-CoV-2 resistance mutation to Remdesivir, associated with virological recrudesce in an immunocompromised patient with persistent COVID-19.

Bibliographic Details
Main Authors: Shiv Gandhi, Jonathan Klein, Alexander J. Robertson, Mario A. Peña-Hernández, Michelle J. Lin, Pavitra Roychoudhury, Peiwen Lu, John Fournier, David Ferguson, Shah A. K. Mohamed Bakhash, M. Catherine Muenker, Ariktha Srivathsan, Elsio A. Wunder, Nicholas Kerantzas, Wenshuai Wang, Brett Lindenbach, Anna Pyle, Craig B. Wilen, Onyema Ogbuagu, Alexander L. Greninger, Akiko Iwasaki, Wade L. Schulz, Albert I. Ko
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29104-y

Internet

https://doi.org/10.1038/s41467-022-29104-y

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