Phenotypic and Functional Profiles of Antigen-Specific CD4+ and CD8+ T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis

Phenotypic and Functional Profiles of Antigen-Specific CD4+ and CD8+ T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis

The host immunological response is a key factor determining the pathogenesis of cutaneous leishmaniasis. It is known that a Th1 cellular response is associated with infection control and that antigen-specific memory T cells are necessary for the development of a rapid and strong protective cellular...

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Bibliographic Details
Main Authors: Adriana Egui, Darién Ledesma, Elena Pérez-Antón, Andrés Montoya, Inmaculada Gómez, Sara María Robledo, Juan José Infante, Ivan Darío Vélez, Manuel C. López, M. Carmen Thomas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leishmania
leishmaniasis
paraflagellar rod protein-1
biomarkers
CD8+ and CD4+ T-cells
phenotype
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00393/full

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https://www.frontiersin.org/article/10.3389/fcimb.2018.00393/full

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