NKX2-8/PTHrP Axis-Mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

NKX2-8/PTHrP Axis-Mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Bone metastasis is one of the most common distant metastasis of breast cancer, which could cause serious skeletal disease and increased cancer-related death. Therefore, identification of novel target(s) to develop therapeutics would improve patient outcomes. The role of NKX2-8 in modulation of bone...

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Bibliographic Details
Main Authors: Ainiwaerjiang Abudourousuli, Suwen Chen, Yameng Hu, Wanying Qian, Xinyi Liao, Yingru Xu, Libing Song, Shuxia Zhang, Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
NKX2-8
breast cancer
bone metastasis
osteoclastogenesis
PTHrP
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.907000/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.907000/full

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