Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington’s disease

Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington’s disease

Introduction: Strong evidence suggests a significant role for iron accumulation in the brain in addition to the well-documented neurodegenerative aspects of Huntington’s disease (HD). The putative mechanisms by which iron is linked to the HD pathogenesis are multiple, including oxidative stress, fer...

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Bibliographic Details
Main Authors: Nadine Anniek van de Zande, Marjolein Bulk, Chloé Najac, Louise van der Weerd, Jeroen de Bresser, Jan Lewerenz, Itamar Ronen, Susanne Tamara de Bot
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Huntington’s disease
Biomarkers
Iron accumulation
Neuroinflammation
MRI
CSF
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223001390

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http://www.sciencedirect.com/science/article/pii/S2213158223001390

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