Utility of Animal Models to Understand Human Alzheimer’s Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals

Utility of Animal Models to Understand Human Alzheimer’s Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals

To diagnose and treat early-stage (preclinical) Alzheimer’s disease (AD) patients, we need body-fluid-based biomarkers that reflect the processes that occur in this stage, but current knowledge on associated processes is lacking. As human studies on (possible) onset and early-stage AD would be extre...

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Bibliographic Details
Main Authors: Tian Qin, Samantha Prins, Geert Jan Groeneveld, Gerard Van Westen, Helga E. de Vries, Yin Cheong Wong, Luc J.M. Bischoff, Elizabeth C.M. de Lange
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
early diagnosis
body fluids
biomarker
animal models
Online Access:https://www.mdpi.com/1422-0067/21/9/3158

Internet

https://www.mdpi.com/1422-0067/21/9/3158

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