Influence of Canonical and Non-Canonical IFNLR1 Isoform Expression on Interferon Lambda Signaling

Influence of Canonical and Non-Canonical IFNLR1 Isoform Expression on Interferon Lambda Signaling

Interferon lambdas (IFNLs) are innate immune cytokines that induce antiviral cellular responses by signaling through a heterodimer composed of IL10RB and the interferon lambda receptor 1 (IFNLR1). Multiple <i>IFNLR1</i> transcriptional variants are expressed in vivo and are predicted to...

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Bibliographic Details
Main Authors: John Grayson Evans, Laura A. Novotny, Eric G. Meissner
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
interferons
interferon lambda receptor 1
innate immunity
antiviral
inflammation
Online Access:https://www.mdpi.com/1999-4915/15/3/632

Internet

https://www.mdpi.com/1999-4915/15/3/632

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