A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions

A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions

Inadequate representation of the human tissue environment during a preclinical screen can result in inaccurate predictions of compound effects. Consequently, pharmaceutical investigators are searching for preclinical models that closely resemble original tissue for predicting clinical outcomes.The c...

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Bibliographic Details
Main Authors: Alexandra Duque-Fernandez, Lydia Gauthier, Mélissa Simard, Jessica Jean, Isabelle Gendreau, Alexandre Morin, Jacques Soucy, Michèle Auger, Roxane. Pouliot
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Pathogenesis
3D-psoriatic skin model
Culture conditions
Physical characterization of the stratum corneum
FTIR experiments
Percutaneous absorption
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580816301996

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http://www.sciencedirect.com/science/article/pii/S2405580816301996

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