BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control

BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control

Background Cancer immunotherapies can produce complete therapeutic responses, however, outcomes in ovarian cancer (OC) are modest. While adoptive T-cell transfer (ACT) has been evaluated in OC, durable effects are rare. Poor therapeutic efficacy is likely multifactorial, stemming from limited antige...

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Bibliographic Details
Main Authors: Kunle Odunsi, Takemasa Tsuji, Mark Long, Danuta Kozbor, Scott I Abrams, Emese Zsiros, A J Robert McGray, Jessie L Chiello, Kathryn Maraszek, Nicole Gaulin, Spencer R Rosario, Suzanne M Hess
Format: Article
Language:English
Published: BMJ Publishing Group 2023-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/6/e006863.full

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https://jitc.bmj.com/content/11/6/e006863.full

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