Enzymatic kinetic method for determination of propranolol hydrochloride in pharmaceuticals based on its inhibitory effect on cholinesterase

Propranolol, a widely used beta-blocker, inhibits the reaction of enzyme cholinesterase hydrolysis. Measurements of the hydrolysis rate differences between and inhibited reactions, allows the development of a kinetic method for its determination. Both systems, enzyme-substrate-chromogen and enzy...

Full description

Bibliographic Details
Main Authors: Mandić Ljuba M., Mitić Violeta D., Ilić Marija D., Stankov-Jovanović Vesna P., Nikolić-Mandić Snežana D.
Format: Article
Language:English
Published: Association of Chemical Engineers of Serbia 2012-01-01
Series:Hemijska Industrija
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0367-598X/2012/0367-598X1200032S.pdf