Optimizing moxidectin dosing for Strongyloides stercoralis infections: Insights from pharmacometric modeling

Abstract Moxidectin is a frontrunner drug candidate in the treatment of strongyloidiasis. A dose of 8 mg is recommended to treat this indication, which shows a reasonably good efficacy and tolerability profile. Yet, owing to the unique life cycle of Strongyloides stercoralis (S. stercoralis) that en...

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Bibliographic Details
Main Authors: Daniela Hofmann, Cornelis Smit, Somphou Sayasone, Marc Pfister, Jennifer Keiser
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13189