Optimizing moxidectin dosing for Strongyloides stercoralis infections: Insights from pharmacometric modeling
Abstract Moxidectin is a frontrunner drug candidate in the treatment of strongyloidiasis. A dose of 8 mg is recommended to treat this indication, which shows a reasonably good efficacy and tolerability profile. Yet, owing to the unique life cycle of Strongyloides stercoralis (S. stercoralis) that en...
Main Authors: | Daniela Hofmann, Cornelis Smit, Somphou Sayasone, Marc Pfister, Jennifer Keiser |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-03-01
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Series: | Clinical and Translational Science |
Online Access: | https://doi.org/10.1111/cts.13189 |
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