Integrin expression in esophageal squamous cell carcinoma: loss of the physiological integrin expression pattern correlates with disease progression.

The integrins are a family of heterodimeric transmembrane signaling receptors that mediate the adhesive properties of epithelial cells affecting cell growth and differentiation. In many epithelial malignancies, altered integrin expression is associated with tumor progression and often correlates wit...

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Bibliographic Details
Main Authors: Christian Vay, Stefan B Hosch, Nikolas H Stoecklein, Christoph A Klein, Daniel Vallböhmer, Björn-Christian Link, Emre F Yekebas, Jakob R Izbicki, Wolfram T Knoefel, Peter Scheunemann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232252?pdf=render