Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells

Summary Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper f...

Descripció completa

Dades bibliogràfiques
Autors principals:	Ying Li, Hailing Hao, Evangeline Tzatzalos, Ren-Kuo Lin, Sungtae Doh, Leroy F. Liu, Yi Lisa Lyu, Li Cai
Format:	Article
Idioma:	English
Publicat:	The Company of Biologists 2014-01-01
Col·lecció:	Biology Open
Matèries:	Cell survival Gene regulation Postmitotic cells Retina Top2b Transcription Retina degeneration
Accés en línia:	http://bio.biologists.org/content/3/2/172

Ítems similars

Retinal ganglion cells undergo cell type—specific functional changes in a computational model of cone-mediated retinal degeneration
per: Aiwen Xu, et al.
Publicat: (2023-05-01)

Comparing optogenetic approaches to visual restoration in a model of retinal degeneration
per: Gilhooley, MJ
Publicat: (2019)

Ciliated, Mitochondria-Rich Postmitotic Cells are Immune-privileged, and Mimic Immunosuppressive Microenvironment of Tumor-Initiating Stem Cells: From Molecular Anatomy to Molecular Pathway
per: Babak Behnam, et al.
Publicat: (2023-10-01)

Developing gene therapy for inherited retinal degenerations
per: Yusuf, IH
Publicat: (2022)

Retinal changes in an ATP-induced model of retinal degeneration
per: Felix Peter Aplin, et al.
Publicat: (2016-04-01)

Retinal Cell Regeneration by Stem Cells
per: Fatemeh Nazem-Roaya, et al.
Publicat: (2015-05-01)

Microglia are not required for prion-induced retinal photoreceptor degeneration
per: James F. Striebel, et al.
Publicat: (2019-03-01)

An insight on established retinal injury mechanisms and prevalent retinal stem cell activation pathways in vertebrate models
per: Rinchen Doma Sherpa, et al.
Publicat: (2021-09-01)

Microglia depletion/repopulation does not affect light-induced retinal degeneration in mice
per: Nils Laudenberg, et al.
Publicat: (2024-01-01)

Age-related functional and structural retinal modifications in the Igf1−/− null mouse
per: L. Rodriguez-de la Rosa, et al.
Publicat: (2012-05-01)

Heparin-Binding Epidermal-like Growth Factor (HB-EGF) Reduces Cell Death in an Organoid Model of Retinal Damage
per: Michelle N. H. Tang, et al.
Publicat: (2024-07-01)

Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degeneration
per: Kaitryn E. Ronning, et al.
Publicat: (2022-12-01)

Galectin-3 Promotes Müller Glia Clearance Phagocytosis via MERTK and Reduces Harmful Müller Glia Activation in Inherited and Induced Retinal Degeneration
per: Deborah S. Lew, et al.
Publicat: (2022-05-01)

Bottlenecks in the Investigation of Retinal Sterol Homeostasis
per: Sriganesh Ramachandra Rao, et al.
Publicat: (2024-03-01)

A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting
per: Elisa Murenu, et al.
Publicat: (2021-03-01)

Retina /
per: Ryan, Stephen J., 1940-
Publicat: (2006)

Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration
per: Ping-Wu Zhang, et al.
Publicat: (2025-01-01)

Lycii Fructus, a medicine food homology material, attenuates retinal damage in sodium iodate-induced retinal degeneration mice and inhibits oxidation-induced apoptosis of Müller cells via regulating Nrf2-HO1 signaling pathway
per: Cheng Cao, et al.
Publicat: (2023-09-01)

Age-Related Changes of the Synucleins Profile in the Mouse Retina
per: Sarah Batista Dias, et al.
Publicat: (2023-01-01)

Extracellular vesicles: an emerging player in retinal homeostasis
per: Amit Chatterjee, et al.
Publicat: (2023-04-01)

Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network
per: Joaquín Letelier, et al.
Publicat: (2023-05-01)

Editorial: Novel frontiers of retinal neurodegenerative diseases
per: Wensheng Li, et al.
Publicat: (2024-08-01)

The Interplay between Peripherin 2 Complex Formation and Degenerative Retinal Diseases
per: Lars Tebbe, et al.
Publicat: (2020-03-01)

Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones
per: Duygu Karademir, et al.
Publicat: (2022-04-01)

Quiescence unveils a novel mutational force in fission yeast
per: Serge Gangloff, et al.
Publicat: (2017-12-01)

Macroaneurisma arterial retinal. Presentación de un caso.
per: Aimé Broche Hernández, et al.
Publicat: (2011-08-01)

Neuroprotective Potential of Pituitary Adenylate Cyclase Activating Polypeptide in Retinal Degenerations of Metabolic Origin
per: Robert Gábriel, et al.
Publicat: (2019-10-01)

Stem cell transplantation for retinal degeneration: current status and future prospects
per: LIU Yong
Publicat: (2019-02-01)

Intravitreal Delivery of Melatonin Is Protective Against the Photoreceptor Loss in Mice: A Potential Therapeutic Strategy for Degenerative Retinopathy
per: Chong Li, et al.
Publicat: (2020-02-01)

The Role of Transcription Factors in Regulating the Development and Differentiation of Neural Retina Cells
per: Razeih Heidari, et al.
Publicat: (2015-11-01)

Reading visual Braille with a retinal prosthesis
per: Thomas Zaccarin Lauritzen, et al.
Publicat: (2012-11-01)

Potential Treatment of Retinal Diseases with Iron Chelators
per: Wanting Shu, et al.
Publicat: (2018-10-01)

Retinal Map of Peripheral Retinal Degenerations and Tears. Part 2. Non-rhegmatogenous Chorioretinal Degenerations
per: V. A. Shaimova, et al.
Publicat: (2024-10-01)

Metabolomic Study of a Rat Model of Retinal Detachment
per: Xiangjun She, et al.
Publicat: (2022-11-01)

Neural Stem Cells/Neuronal Precursor Cells and Postmitotic Neuroblasts in Constitutive Neurogenesis and After ,Traumatic Injury to the Mesencephalic Tegmentum of Juvenile Chum Salmon, <i>Oncorhynchus keta</i>
per: Evgeniya V. Pushchina, et al.
Publicat: (2020-01-01)

The adult retinal stem cell is a rare cell in the ciliary epithelium whose progeny can differentiate into photoreceptors
per: Brian G. Ballios, et al.
Publicat: (2012-02-01)

Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases
per: Hang Liu, et al.
Publicat: (2024-10-01)

Highly efficient generation of glutamatergic/cholinergic NT2-derived postmitotic human neurons by short-term treatment with the nucleoside analogue cytosine β-d-arabinofuranoside
per: Imanol González-Burguera, et al.
Publicat: (2016-03-01)

The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against N-Methyl-N-Nitrosourea Induced Retinal Degeneration: A Topographic Study
per: Ye Tao, et al.
Publicat: (2017-08-01)

Influence of age on the thickness of retinal nerve fiber layer in patients with mild-to-moderate stages of Parkinson’s disease: Case series
per: Eric Pinheiro de Andrade, et al.
Publicat: (2024-03-01)