Enhanced TrkA signaling impairs basal forebrain-dependent behavior

Enhanced TrkA signaling impairs basal forebrain-dependent behavior

Basal forebrain cholinergic neurons (BFCNs) modulate cognitive functions such as attention, learning and memory. The NGF/TrkA pathway plays an important role in the development and function of BFCNs, although two mouse models conditionally deleting TrkA expression in the central nervous system (CNS)...

Full description

Bibliographic Details
Main Authors: Laura Calvo-Enrique, Silvia Lisa, Cristina Vicente-García, Ruben Deogracias, Juan Carlos Arévalo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
TrkA
NGF (nerve growth factor)
basal forebrain
cholinergic neurons
mice behavior
learning
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1266983/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1266983/full

Similar Items