Enhanced TrkA signaling impairs basal forebrain-dependent behavior

Enhanced TrkA signaling impairs basal forebrain-dependent behavior

Basal forebrain cholinergic neurons (BFCNs) modulate cognitive functions such as attention, learning and memory. The NGF/TrkA pathway plays an important role in the development and function of BFCNs, although two mouse models conditionally deleting TrkA expression in the central nervous system (CNS)...

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Bibliographic Details
Main Authors:	Laura Calvo-Enrique, Silvia Lisa, Cristina Vicente-García, Ruben Deogracias, Juan Carlos Arévalo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	TrkA NGF (nerve growth factor) basal forebrain cholinergic neurons mice behavior learning
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1266983/full

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