An Overall Comparison of Small Molecules and Large Biologics in ADME Testing

Biologics mainly monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) as new therapeutics are becoming increasingly important biotherapeutics. This review is intended to provide an overall comparison between small molecules (SMs) and biologics or large molecules (LMs) concerning drug met...

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Bibliographic Details
Main Author: Hong Wan
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2016-03-01
Series:ADMET and DMPK
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/276