Advances in the DNA methylation hydroxylase TET1

Advances in the DNA methylation hydroxylase TET1

Abstract Background The ten-eleven translocation 1 (TET1) protein is a 5-methylcytosine hydroxylase that belongs to the TET protein family of human α-ketoglutarate oxygenases. TET1 recognizes and binds to regions of high genomic 5′-CpG-3′ dinucleotide density, such as CpG islands, initiates the DNA...

Full description

Bibliographic Details
Main Authors: Wenzheng Liu, Guanhua Wu, Fei Xiong, Yongjun Chen
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Biomarker Research
Subjects:
Ten-eleven translocation 1
DNA demethylation
Stem cells
Immunity
Clinical disease
Malignant tumours
Online Access:https://doi.org/10.1186/s40364-021-00331-7

Internet

https://doi.org/10.1186/s40364-021-00331-7

Similar Items