RNA sequencing and bioinformatics analysis of differentially expressed genes in the peripheral serum of ankylosing spondylitis patients

Abstract Background Ankylosing spondylitis (AS) is a chronic progressive autoimmune disease characterized by spinal and sacroiliac arthritis, but its pathogenesis and genetic basis are largely unclear. Methods We randomly selected three serum samples each from an AS and a normal control (NC) group f...

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Bibliographic Details
Main Authors: Yongchen Bie, Xiujun Zheng, Xiaojiong Chen, Xiangyun Liu, Liqin Wang, Yuanliang Sun, Jianqiang Kou
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03871-w