Preparation of pH-sensitive nanogels bioconjugated with shark antibodies (VNAR) for targeted drug delivery with potential applications in colon cancer therapies.

Cancer is the second leading cause of death worldwide. To combat this disease, novel and specialized therapeutic systems are urgently needed. This is the first study to explore a system that combines shark variable domain (Fv) of new antigen receptor (VNAR) antibodies (hereinafter VNARs), PEGylated...

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Bibliographic Details
Main Authors: Lizbeth A Manzanares-Guevara, Jahaziel Gasperin-Bulbarela, Olivia Cabanillas-Bernal, Monserrat Renteria-Maciel, Angel Licea-Claverie, Eugenio R Méndez, Alexei F Licea-Navarro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294874&type=printable