Downregulation of monocyte miRNAs: implications for immune dysfunction and disease severity in drug-resistant tuberculosis

Downregulation of monocyte miRNAs: implications for immune dysfunction and disease severity in drug-resistant tuberculosis

BackgroundMonocyte miRNAs govern both protective and pathological responses during tuberculosis (TB) through their differential expression and emerged as potent targets for biomarker discovery and host-directed therapeutics. Thus, this study examined the miRNA profile of sorted monocytes across the...

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Bibliographic Details
Main Authors: Pavithra Sampath, Manju Moorthy, Athul Menon, Lekshmi Madhav, Aishwarya Janaki, Madhavan Dhanapal, Alangudi Palaniappan Natarajan, Syed Hissar, Uma Devi Ranganathan, Gopalakrishna Ramaswamy, Ramalingam Bethunaickan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
monocyte miRNA
drug-resistant -TB
immune dysfunction
Mycobacterium tuberculosis
NanoString
monocyte sorting
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197805/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197805/full

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