Acute oral toxicity and antimalarial studies of 7-[(7-methoxy-4,5-dihydro-1H-benzo[g]indazol-3-yl)carbonyl]-2-phenyl-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one in mouse models
Reports of resistance to current antimalarial combination therapies (ACTs) have necessitated the discovery of new antimalarial drugs, most importantly with new mechanisms of action. From our molecular docking study, the small molecule 7-[(7-methoxy-4,5-dihydro-1H-benzo[g]indazol-3-yl)carbonyl]-2-phe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
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Series: | Scientific African |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227624001406 |