The microbial capsular polysaccharide galactoxylomannan inhibits IL-17A production in circulating T cells from rheumatoid arthritis patients.

The persistence of activated T cells in rheumatoid arthritis (RA) synovium may be attributable to increased homing, increased retention or a possible imbalance between cell proliferation and programmed cell death. Induction of apoptosis may represent a potential therapeutic approach. Galactoxylomann...

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Bibliographic Details
Main Authors: Eva Pericolini, Alessia Alunno, Elena Gabrielli, Elena Bartoloni, Elio Cenci, Siu-Kei Chow, Giovanni Bistoni, Arturo Casadevall, Roberto Gerli, Anna Vecchiarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3540098?pdf=render