Design of VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1): A double-blind, randomized placebo-controlled trial of COVID-19 convalescent plasma in hospitalized patients with early respiratory compromise

Design of VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1): A double-blind, randomized placebo-controlled trial of COVID-19 convalescent plasma in hospitalized patients with early respiratory compromise

Background: Effective therapeutics for severe acute respiratory syndrome CoronaVirus-2 (SARS-CoV-2) infection are evolving. Under Emergency Use Authorization, COVID-19 convalescent plasma (CCP) was widely used in individuals hospitalized for COVID-19, but few randomized controlled trials supported i...

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Bibliographic Details
Main Authors: Edward N. Janoff, Sheldon T. Brown, Ilana Belitskaya-Levy, Jeffrey L. Curtis, Robert A. Bonomo, Elliott K. Miller, Alexa M. Goldberg, Lisa Zehm, Ashlea Wills, Caitlin Hutchinson, Larry J. Dumont, Theresa Gleason, Mei-Chiung Shih
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Contemporary Clinical Trials Communications
Subjects:
COVID-19
Convalescent plasma
Randomized controlled trial
Hypoxemia
Respiratory failure
WHO ordinal scale
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865423001369

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http://www.sciencedirect.com/science/article/pii/S2451865423001369

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