Ultrastructure in Transthyretin Amyloidosis: From Pathophysiology to Therapeutic Insights

Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has traditionally been termed senile systemic amyloidosis, while ATTRv amyloidosis has been called familial amyloid polyneuropathy. Although...

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Bibliographic Details
Main Authors: Haruki Koike, Masahisa Katsuno
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/7/1/11