The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory cytokine, protecting the body from an uncontrolled immune response, mostly through the Jak1/Tyk2 and STAT3 signaling...

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Bibliographic Details
Main Authors: Valentina Carlini, Douglas M. Noonan, Eslam Abdalalem, Delia Goletti, Clementina Sansone, Luana Calabrone, Adriana Albini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
IL-10
STAT3
cytokine storm
alarmin
COVID - 19
Post-COVID
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1161067/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1161067/full

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