Targeting DNA damage response deficiency in the treatment of breast cancer

DNA damage response (DDR) deficiency has been one of the emerging targets in treating breast cancer in recent years. The DDR pathway is essential for the identification, signal transduction and repair of DNA damage. Its dysfunction may lead to cell apoptosis or genomic instability. Poly (ADP-ribose)...

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Bibliographic Details
Main Author: JIN Yizi, LIN Mingxi, ZHANG Jian
Format: Article
Language:English
Published: Editorial Office of China Oncology 2022-01-01
Series:Zhongguo aizheng zazhi
Subjects:
Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/1643099040245-23748981.pdf