Targeting DNA damage response deficiency in the treatment of breast cancer
DNA damage response (DDR) deficiency has been one of the emerging targets in treating breast cancer in recent years. The DDR pathway is essential for the identification, signal transduction and repair of DNA damage. Its dysfunction may lead to cell apoptosis or genomic instability. Poly (ADP-ribose)...
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Format: | Article |
Language: | English |
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Editorial Office of China Oncology
2022-01-01
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Series: | Zhongguo aizheng zazhi |
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Online Access: | http://www.china-oncology.com/fileup/1007-3639/PDF/1643099040245-23748981.pdf |