A novel ex-vivo isolated rabbit heart preparation to explore the cardiac effects of cervical and cardiac vagus nerve stimulation

Abstract The cardiac responses to vagus nerve stimulation (VNS) are still not fully understood, partly due to uncontrollable confounders in the in-vivo experimental condition. Therefore, an ex-vivo Langendorff-perfused rabbit heart with intact vagal innervation is proposed to study VNS in absence of...

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Bibliographic Details
Main Authors: Bettina Kronsteiner, Max Haberbusch, Philipp Aigner, Anne-Margarethe Kramer, Patrick M. Pilz, Bruno K. Podesser, Attila Kiss, Francesco Moscato
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31135-4