Frizzled class receptor 5 contributes to ovarian cancer chemoresistance through aldehyde dehydrogenase 1A1

Frizzled class receptor 5 contributes to ovarian cancer chemoresistance through aldehyde dehydrogenase 1A1

Abstract Background Chemoresistance is associated with tumor relapse and unfavorable prognosis. Multiple mechanisms underlying chemoresistance have been elucidated, including stemness and DNA damage repair. Here, the involvement of the WNT receptor, FZD5, in ovarian cancer (OC) chemoresistance was i...

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Bibliographic Details
Main Authors: Yuhong Xia, Shan Wang, Yu Sun, Wei Wang, Shijie Chang, Zhongbo Zhang, Chenghai Zhao
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Cell Communication and Signaling
Subjects:
Chemoresistance
Stemness
Homologous recombination repair
DNA-damaging therapy
Ovarian cancer
Online Access:https://doi.org/10.1186/s12964-024-01585-y

Internet

https://doi.org/10.1186/s12964-024-01585-y

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