2D QSAR studies of the inhibitory activity of a series of substituted purine derivatives against c-Src tyrosine kinase
A series of 34 substituted purine analogues derivatives were subjected to quantitative structure-activity relationship analyses as inhibitors of c-Src tyrosine kinase. Partial least squares regression was applied to derive QSAR models, which were further validated for statistical significance by int...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2016-07-01
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| Series: | Journal of Taibah University for Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1658365515001776 |