Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

Background: Clopidogrel is frequently used in patients with ischemic stroke or transient ischemic attack (TIA), but its efficacy is hampered by inter-individual variability, due to genetic differences associated with clopidogrel metabolism. We conducted this randomized controlled trial to validate w...

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Bibliographic Details
Main Authors: Xiaoguang Zhang, Shanshan Jiang, Jie Xue, Ying Ding, Jingyu Gu, Liang Hu, Xushen Xu, Zhizhang Li, Yuming Kong, Youmei Li, Xiaoqiong Zhu, Yunhua Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
ischemic stroke
transient ischemic attack
clopidogrel
pharmacogenomics
randomized controlled trial
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.931405/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.931405/full

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