PO2 oscillations induce lung injury and inflammation

PO2 oscillations induce lung injury and inflammation

Abstract Background Mechanical ventilation can lead to ventilator-induced lung injury (VILI). In addition to the well-known mechanical forces of volutrauma, barotrauma, and atelectrauma, non-mechanical mechanisms have recently been discussed as contributing to the pathogenesis of VILI. One such mech...

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Bibliographic Details
Main Authors: Stefan Boehme, Erik K. Hartmann, Thomas Tripp, Serge C. Thal, Matthias David, Dietmar Abraham, James E. Baumgardner, Klaus Markstaller, Klaus U. Klein
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Critical Care
Subjects:
Cyclic recruitment and derecruitment of atelectasis
PO2 oscillations
Ventilator-induced lung injury
Veno-venous extracorporeal membrane oxygenation
Pathomechanism
Lung injury
Online Access:http://link.springer.com/article/10.1186/s13054-019-2401-1

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http://link.springer.com/article/10.1186/s13054-019-2401-1

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