Senkyunolide A inhibits the progression of osteoarthritis by inhibiting the NLRP3 signalling pathway

Context Osteoarthritis (OA) is a degenerative disease. Senkyunolide A (SenA) is an important phthalide from Ligusticum chuanxiong Hort (Umbelliferae) with anti-spasmodic and neuroprotective effects.Objective We explored the effect of SenA on IL-1β-stimulated chondrocytes and OA miceMaterials and met...

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Bibliographic Details
Main Authors: Minglei Shao, Dongwei Lv, Kai Zhou, Haijun Sun, Zhitao Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2042327